This invention relates to boronophthalide compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. Said compounds are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present boronophthalide compounds have physiochemical properties that facilitate penetration of the nail plate.