Donald Landry;Patricia F. Ducy;Yuli Xie;Gerard Karsenty;Vijay Yadav
发明人:
Gerard Karsenty,Patricia F. Ducy,Yuli Xie,Donald Landry,Vijay Yadav
申请号:
US14282177
公开号:
US20150111908A1
申请日:
2014.05.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis and the agents are TPH1 inhibitors or serotonin receptor antagonists.