HARRIS, Paul William Richard,LOOMES, Kerry Martin,HAY, Deborah Lucy,JAMALUDDIN, Aqfan,WALKER, Christopher Stuart,WILLIAMS, Elyse Thomasine,BRIMBLE, Margaret Anne
申请号:
AU2018362018
公开号:
AU2018362018A1
申请日:
2018.11.06
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
Disclosed are peptide conjugates that are calcitonin gene-related peptide (CGRP) receptor antagonists comprising a CGRP peptide, wherein at least one amino acid of the peptide is covalently conjugated to a lipid-containing moiety. Also disclosed are pharmaceutical compositions and kits comprising such conjugates, methods of preparing such conjugates, and uses of such antagonists.