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Polimer pochodny polietylenoiminy liniowej do transferu genów
专利权人:
Universite d'Evry Val d'Essonne;Centre National de la Recherche Scientifique (CNRS);Université d'Orléans
发明人:
CHERADAME, HERVÉ,SASSATELLI, MATHIEU,GUEGAN, PHILIPPE,MIDOUX, PATRICK,PICHON, CHANTAL
申请号:
PL09720962
公开号:
PL2257587T3
申请日:
2009.03.04
申请国别(地区):
PL
年份:
2020
代理人:
摘要:
The invention relates to a static copolymer of linear polyethylenimine that comprises two monomer units of the following formulas I and II, in which R1 is a hydrogen atom or a C1-C6 alkyl radical, R2 is a hydrogen atom, a C1-C6 alkyl, aryl or aralkyl group, wherein the alkyl group is a C1-C6 one, n is a number between 1 and 99% of the total monomers, m is a number between 1 and 99% of the total monomers, and advantageously m+n=100%. The invention also relates to complexes of this copolymer with a nucleic acid, and to the use thereof in in vivo, in vitro or ex vivo gene transfection.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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