Systems and methods for processing portable wavefront aberrometer data are disclosed. In one embodiment, a method includes receiving, from a mobile computing device, image data captured by a light detector of the mobile computing device, the image data corresponding to light reflected from an eye of a patient and passed through a portable wavefront aberrometer coupled to the mobile computing device. The method further includes processing the image data to compute a patient-specific parameter associated with the patient, and transmitting the patient-specific parameter to one or more of the mobile computing device or a computing device associated with a medical provider.