Selina Chen-Kiang,Maurizio Di Liberto,Xiangao Huang
申请号:
US12741884
公开号:
US09259399B2
申请日:
2008.10.01
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention involves methods of inhibiting the cancer cell cycle to make cancer cells more susceptible to chemotherapeutic agents. In particular, inhibition of CDK4 and/or CDK6 inhibits cell cycle progression in cancer cells. When combined with chemotherapy such cell cycle inhibition can effectively treat even aggressive cancer types that are drug-resistant and intractable to most chemotherapies.