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TEMPERATURE-, PH- OR SALT CONCENTRATION-SENSITIVE SEPARATION MATERIAL AND USE THEREOF
专利权人:
Naoko Shimada
发明人:
Naoko Shimada,Atsushi Maruyama
申请号:
US13636436
公开号:
US20130012597A1
申请日:
2011.03.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides a UCST-type thermoresponsive polymer compound which responds to a temperature under physiological conditions and has biofunctionality, and various uses thereof as a thermoresponsive material. Specifically, the invention provides a thermoresponsive material containing, as an active ingredient, a polymer compound represented by Formula (I) below or an addition salt thereof, the thermoresponsive material having an upper critical solution temperature in the range of 5 to 50° C. in an aqueous solution with a salt concentration of at least 1 mM and a pH in the range of 3 to 10.5:wherein m represents an integer of 10 or more n represents a number satisfying 0.4≦n≦1 R1 represents hydrogen or succinyl and R2 represents carbamoyl.
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