PATTERSON, JOHN BRUCE,LONERGAN, DAVID GREGORY,FLYNN, GARY A.,ZENG, QINGPING,PALLAI, PETER V.
申请号：
CA2690913
公开号：
CA2690913C
申请日:
2008.06.09
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Compounds which directly inhibit IRE- 1.alpha. activity in vitro, prodrugs,andpharmaceutically acceptable salts thereof. These compounds are represented byformula (B):(see formula B)Such compounds and prodrugs are useful for treating diseases associated withtheunfolded protein response and can be used as single agents or in combinationtherapies.
