FUNDACIÓ PRIVADA INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS (ICREA);UNIVER;FUNDACIÓ INSTITUTE DE BIOENGINYERIA DE CATALUNYA (IBEC);FUNDACIÓ CENTRE DE MEDICINA REGENERATIVA DE BARCELONA (CMRB)
发明人:
Elena Martínez Fraiz,Ángel Raya Chamorro,Raimon Jané Campos,Maria Valls Margarit,Olalla Iglesias García
申请号：
US16431593
公开号：
US20190365951A1
申请日:
2019.06.04
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure relates to a human cardiac tissue construct, to the method for producing thereof and its uses in disease modelling, compound screening and properties evaluation, and/or therapeutic uses in heart regeneration. It further relates to a perfusion bioreactor with electrical stimulation capabilities and its use in the production of said human cardiac tissue construct. In still a further aspect, the disclosure provides a method for the non-destructive evaluation of electrophysiological activity in a cellular construct, such as a cardiac tissue construct of the disclosure.
