Halilovic, Ensar,Caponigro, Giordano,Horn-Spirohn, Thomas,Lehar, Joseph
申请号:
AU2016314082
公开号:
AU2016314082A1
申请日:
2016.08.24
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present disclosure relates to a pharmaceutical combination comprising (a) an Mdm2 inhibitor and (b)(i) a MEK inhibitor and/or (b)(ii) Bcl2 inhibitor, particularly for use in the treatment of a cancer. This disclosure also relates to uses of such combination for preparation of a medicament for the treatment of a cancer; methods of treating a cancer in a subject in need thereof comprising administering to said subject a jointly therapeutically effective amount of said combination; pharmaceutical compositions comprising such combination and commercial packages thereto.