Julie Ann Spicer;Joseph Albert Trapani;Mark John Smyth;Dani Michelle Lyons;Kristiina Maria Huttunen;William Alexander Denny
发明人:
Julie Ann Spicer,Kristiina Maria Huttunen,Dani Michelle Lyons,Joseph Albert Trapani,Mark John Smyth,William Alexander Denny
申请号:
US13519096
公开号:
US20130065897A1
申请日:
2010.12.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides novel compounds of the Formula I, pharmaceutical compositions comprising such compounds and methods for using such compounds as agents or drugs for inhibiting perforin activity and for treating a subject at risk of or susceptible to a disease or disorder, or having a disease or disorder associated with undesirable perforin activity.