Onishchenko Aleksandr Leonidovich (RU),Онищенко Александр Леонидович (RU),Popova Anna Sergeevna (RU),Попова Анна Сергеевна (RU),Zorina Raisa Mikhajlovna (RU),Зорина Раиса Михайловна (RU),Kolbasko Anat
申请号：
RU2017144470
公开号：
RU0002675690C1
申请日:
2017.12.18
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to ophthalmology, and can be used to predict the risk of developing postoperative inflammation following cataract phacoemulsification. In preparation for surgical treatment, three days before the operation, an additional diagnostic study of the protein composition of the patients tear fluid is carried out. Content of alpha-2-macroglobulin and immunoglobulin G in the obtained sample is determined by enzyme-linked immunosorbent assay. Calculate the coefficient by the formula: K = a2-MG (mg/l) × IgG (mg/l). When the value of the coefficient K>6.3, predict the risk of postoperative inflammation following cataract phacoemulsification as high, recommend additional treatment and postpone the date of surgical treatment. When the value of the coefficient K<6.3, predict the risk of developing postoperative inflammation as low, carry out surgical treatment without additional preoperative drug treatment.EFFECT: method provides a timely forecast of postoperative inflammatory reaction in the eyeball following cataract phacoemulsification, preservation of the visual functions of patients, minimizing the timing of their visual rehabilitation by determining the content of alpha-2-macroglobulin and immunoglobulin G in a tear fluid sample using a non-traumatic, minimally invasive and highly specific method of enzyme-linked immunosorbent assay and calculating the prognostic significant factor K.1 cl, 1 tbl, 3 exИзобретение относится к медицине, а именно к офтальмологии, и может быть использовано для прогнозирования риска развития послеоперационного воспаления после факоэмульсификации катаракты. При подготовке к оперативному лечению за три дня до операции дополнительно проводят диагностическое исследование белкового состава слезной жидкости пациента. Определяют содержание альфа-2-макроглобулина и иммуноглобулина G в полученном образце методом твердофазного иммуноферментного анализа. Рассчитывают коэффициент по формуле: К =
