George MONIZ,Kristen SANDERS,Arani CHANDA,Kenshi YOSHIDA
申请号:
US15566527
公开号:
US20180093972A1
申请日:
2016.04.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A number of crystalline forms of N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl)phenyl)acrylamide are provided. These include a crystalline free base form, a crystalline monohydrochloride salt form, a crystalline dihydrochloride salt form, and a crystalline ethanesulfonate salt form. Methods of making and using crystalline compounds are also provided.