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Aqueous topical formulation comprising an antiangiogenic drug that is an anti VEGF Antibody and a liposome consists of a Lipid based Peg; its use in the treatment of a disease or condition related to VEGF, and Method for treating cancer, psoriasis, diabetic macular edema, among ot Ras diseases.
专利权人:
LLC;OPKO PHARMACEUTICALS
发明人:
SANTOS ARTURO,FROST PHILLIP
申请号:
CL2015000418
公开号:
CL2015000418A1
申请日:
2015.02.20
申请国别(地区):
CL
年份:
2015
代理人:
摘要:
The present invention relates to pharmaceutical formulations comprising an anti angiogenic compound such as a monoclonal antibody or fragment thereof selected from, for example, ranibizumab, which is a vascular endothelial growth factor binder which inhibits the action of VEGF, and a delivery agent selected from a pharmaceutically acceptable liposome. The formulations are useful in the treatment of a variety of angiogenic disorders and diseases in animals and people, and, preferably, in ophthalmic disorders selected from age-related macular degeneration, diabetic macular edema and corneal neovascularization.<;p>;LA INVENCIÓ;N PROPORCIONA A UNA FORMULACION ACUOSA TOPICA QUE COMPRENDE UN FARMACO ANTIANGIOGENICO QUE ES UN ANTICUERPO ANTI-VEGF Y UN LIPOSOMA FORMADO DE UN LIPIDO A BASE DE PEG; SU USO EN EL TRATAMIENTO DE UNA ENFERMEDAD O CONDICION RELACIONADA CON VEGF; Y METODO PARA TRATAR CANCER, PSORIASIS Y EDEMA MACULAR DIABETICO, ENTRE OTRAS ENFERMEDADES.<;/p>;
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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