Bryan Frieman;Daniel D. Long;Daisuke Roland Saito;Lan Jiang
发明人:
Daisuke Roland Saito,Daniel D. Long,Lan Jiang,Bryan Frieman
申请号：
US14315582
公开号：
US09199993B2
申请日:
2014.06.26
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds of formula (I):wherein R2, R7, and m are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.
