A composition containing minerals from aloe rind, and more particularly to compositions containing minerals derived from aloe rind by ashing or fermentation, and methods of preparing and using the compositions is disclosed. Formulations can includes aloe rind minerals and one or more additional active on inactive ingredients, and can be suitable for topical or oral administration. Method of maintaining or improving tissue health, for example, maintaining or improving bone health, maintaining or improving cardiovascular health, or improving the appearance or texture of skin by administering the aloe rind minerals are also disclosed.
