Herbert Haack,Katherine Eleanor Crosby,Victoria McGuinness Rimkunas,Matthew Ren Silver
申请号:
US13204342
公开号:
US20120101108A1
申请日:
2011.08.05
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides methods to identify, diagnose, and treat kidney cancer through the detection of expression and/or activity of anaplastic lymphoma kinase (ALK). The detection of the presence of a polypeptide with ALK kinase activity (e.g., by detecting expression and/or activity of the polypeptide), identify those kidney cancers that are likely to respond to an ALK-inhibiting therapeutic.