Methods for treating ailments in a patient in need thereof includes the step of directing a therapeutic, non-inhaled dosage to at least one nasal cavity of the patient through a flow regulating device while the patient refrains from inhaling. The dosage includes a saline fluid and a gas containing carbon dioxide, and, in some dosages, additional active component(s) wherein the therapeutic, non-inhaled dosage is delivered at a specified flow rate the delivery devices are also included.
