A method of producing an adhesive sheet for skin includes attaching a water-absorptive support to a water-permeable biocompatible film to prepare a stack including the biocompatible film and the support, applying an aqueous ink including water and a functional material to the biocompatible film side of the stack thereby to fix the functional material to the biocompatible film, and separating the biocompatible film having the functional material fixed thereto from the support. An adhesive sheet for skin comprises a water-permeable biocompatible film to which an aqueous ink including water and a functional material has been applied and fixed and a water-absorptive support detachably attached to the biocompatible film.