Coombs, Justin Taylor,Barry, Simon Charles,Sadlon, Timothy John
申请号:
AU2016318230
公开号:
AU2016318230A1
申请日:
2016.09.10
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to chimeric antigen receptors (CARs) directed to cells expressing a dysfunctional or non-functional P2X purinoceptor 7 receptor. Further provided are methods of targeting neoplastic cells and tumours expressing a dysfunctional or non- functional P2X purinoceptor 7 receptor and methods of treating and preventing cancer is a subject.