An expandable prosthetic device and method of delivery that allows the initialplacement of multiple guidewires into selected target sites. The prosthesisincludes a main body device. This main body device has a separate side branch guidewirelumen that passes through the main body device and through a side opening in themain body device. As the main body device is advanced, the side opening is selfguided (by the side branch guidewire) and self-aligns to the side branch vesselostium. The main body device is then deployed, leaving the side branch guidewirein place. A side branch device is then advanced along the side branch guidewirethrough the main body device, through the side wall opening and into the nativeside branch vessel. The side branch device can then be deployed to engage the mainbody device and the native side branch vessel.
