PROBLEM TO BE SOLVED: To provide a new GPR119 agonist, and to use the same, e.g., for treating or preventing hyperglycemia.SOLUTION: The GPR119 agonist includes 5-hydroxy-6E, 8Z, 11Z, 14Z, 17Z-eicosapentaenoic acid(5-HEPE) as an active constituent. The insulin secretion promoter, hypoglycemic agent and agent for treating or preventing diabetes include the same.COPYRIGHT: (C)2013,JPO&INPIT【課題】新規なGPR119アゴニストを提供し、それを高血糖の治療・予防などに使用すること。【解決手段】5-hydroxy-6E,8Z,11Z,14Z,17Z-eicosapentaenoic acid(5-HEPE)を有効成分とするGPR119アゴニスト、並びにそれを含むインスリン分泌促進剤、血糖降下剤および糖尿病の治療または予防剤。【選択図】図3
