THERAPIE A BASE D'ANTICORPS A ACTIVITE ADCC RENFORCEE

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专利权人:

GENZYME CORPORATION

发明人:

MCPHERSON, JOHN M.,EDMUNDS, TIM,ZHOU, QUN

申请号：

CA2626556

公开号：

CA2626556C

申请日:

2006.10.20

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Methods for producing antibody-based therapeutics with enhanced ADCC activityare disclosed. The enhanced ADCC activity is attributed to oligomannose- typeN/-glycans on the antibodies and Fc fusion proteins of the invention. Alsodisclosed are methods of using such antibody-based therapeutics for targetedkilling of cells in a mammal, including therapeutic methods of treatingcancers, autoimmune diseases and other diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/