A method of positioning a tip of a pacemaker lead, which has passed through a coronary sinus, into an interventricular septum, in order to effectively transmit electrical stimulus, includes: inserting into a intervention wire through a superior vena cava and a coronary sinus to pass through the interventricular septum and then guiding the intervention wire to an inferior vena cava； and positioning the tip of the lead into the interventricular septum by inserting the pacemaker lead along the intervention wire. An apparatus for positioning a tip of a pacemaker lead, which has passed through a coronary sinus, into an interventricular septum where a conduction system of a heart is positioned, in order to effectively transmit electrical stimulus, includes: a intervention wire connected through a inferior vena cava, a coronary sinus, an interventricular sinus, a right ventricle, and an inferior vena cava； a surgical catheter passing through the inferior vena cava and a safe zone to capture the intervention wire positioned in the right ventricle； and a pacemaker lead inserted along the intervention wire such that the tip is positioned in interventricular septum tissues.
