Amal Wahhab,Eric Therrien,Martin Allan,Sukhdev Manku
申请号：
US12039141
公开号：
US08338437B2
申请日:
2008.02.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to compounds that are useful as inhibitors of protein arginine methyltransferase that have a formula selected from Formula (I), Formula (II) and Formula (III), as well as racemic mixtures, diastereomers, enantiomers and tautomers thereof and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof as defined herein. The compound are useful as inhibitors of PRMTs and/or CARM-I. The invention further relates to compositions comprising such compounds and methods for their use.
