To provide a bacteria-containing oral rapidly disintegrating tablet having exceptional long-term live-cell stability. The present invention was completed by confirming that using a spray drying method in a live-cell granulation process makes it possible to shorten disintegration time and improve live-cell stability.本發明提供一種長時間之活菌穩定性優異的含菌之口腔內快速崩解性錠劑。本發明確認到藉由在活菌之造粒過程中使用噴霧乾燥法,可縮短崩解時間且提昇活菌穩定性,從而完成了本發明。