Bret Berner,Sui Yuen Eddie Hou,Theophilus J. Gana,Marilou S. Cramer
申请号：
US13707961
公开号：
US08592481B2
申请日:
2012.12.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided is a method of treating a patient suffering from a pain state by administering to the patient a gastric retentive dosage form of gabapentin that is capable of administration in once-daily or twice daily dosing regimens. By reducing the need to administer gabapentin from the thrice-daily administrations characteristic of immediate release gabapentin, the gastric retentive gabapentin dosage forms provided herein have the advantages of improving patient compliance for gabapentin treatment. In addition to the foregoing, the gastric retentive gabapentin dosages forms also exhibit decreased blood plasma concentrations and increased bioavailability throughout the dosing regimen.
