Skin compatible curing adhesives for adhering devices or appliances to mammalian body are disclosed. Adhesive compositions to protect per-anal, peri-stomal, peri-wound, and peri-fistula skin are disclosed. The skin compatible curable adhesive includes at least one silylated polymer, silylated macromer, silylated monomer, or a combination thereof at least one curing catalyst and at least one crosslinking agent.
