Matthew J. Kipper,Balaji Narasimhan,Jennifer H. Wilson,Michael J. Wannemuehler
申请号：
US12554282
公开号：
US08173104B2
申请日:
2009.09.04
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms are provided. The copolymer or homopolymer microparticles degrade by surface-erosion from in vivo hydrolysis of anhydride linkages at the surface of the microparticle, which results in controlled release of immunogen(s) to a patient.
