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Azetidine compounds, compositions and methods of use
专利权人:
Hoffman-La Roche Inc.
发明人:
Simona M. Ceccarelli,Carine Guerot,Henner Knust
申请号:
US14328033
公开号:
US09139593B2
申请日:
2014.07.10
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided are compounds of Formula I,R1-L1-A-L2-R2  (I),and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein A, L1, L2, R1 and R2 are defined herein. The present invention also provides a pharmaceutical composition and methods of using such compounds. The compounds are useful for therapy and/or prophylaxis in a patient, and in particular to inhibitors of Soluble Epoxide Hydrolase (sEH).
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