DUOCARMYCIN ADCS FOR USE IN TREATMENT OF ENDOMETRIAL CANCER

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专利权人:

发明人:

申请号：

EP15700211.4

公开号：

EP2948183A2

申请日:

2015.01.09

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention relates to duocarmycin-containing antibody-drug conjugates (ADCs) for use in the treatment of human solid tumors expressing HER2, wherein the human solid tumor expressing HER2 is endometrial cancer, in particular uterine serous carcinoma (USC). In particular, the present invention relates to duocarmycin-containing ADCs for use in the treatment of endometrial cancer, notably USC, with HER2 IHC 2− or 1+ and HER2 FISH negative tumor tissue status.

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中国工程科技知识中心

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http://www.ckcest.cn/home/