Drug delivery system for administering water-soluble, cationic and amphiphilic pharmaceutically active substances

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专利权人:

アーデニア・インベストメンツ・リミテッド

发明人:

アレクソフ，ジュリアン,ロコット，イゴー,アレクソフ,ジュリアン,ロコット,イゴー

申请号：

JP2010539386

公开号：

JP5466173B2

申请日:

2008.12.18

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

A drug delivery system (DDS) for administration of a water soluble, cationic, and amphiphilic pharmaceutically active substance (API) which DDS comprises poorly water soluble nanoparticles formed by the API together with a Na-salt of N-all-trans-retinoyl cysteic acid methyl ester and/or a Na-salt of N-13-cis-retinoyl cysteic acid methyl ester. A pharmaceutical composition comprising such a DDS. Methods for preparation of such a DDS and such a pharmaceutical composition. Use of such a DDS and pharmaceutical composition for treatment of cancer.

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中国工程科技知识中心

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http://www.ckcest.cn/home/