PROBLEM TO BE SOLVED: To provide a proteasome activator which activates proteasome removing abnormal protein.SOLUTION: The proteasome activator comprises silybin maltoside and silymarin as active ingredients. The restorative dealing with reduction in trypsin-like proteasome activity caused by ultraviolet B exposure comprises silybin maltoside and silymarin as active ingredients.COPYRIGHT: (C)2012,JPO&INPIT【課題】プロテアソーム活性化剤を提供する。【解決手段】シリビンマルトシド及びシリマリンを有効成分とするプロテアソーム活性化剤。【選択図】図1