대한민국(농촌진흥청장); LTD.;SUNG KYUN BIOTECH CO., LTD.;RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY;SUNG KYUN BIOTECH CO.;주식회사 성균바이오텍;REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION);성균관대학교산학협력단
发明人:
PARK, KYE WON,박계원,JANG, WOO SEOK,장우석,KIM, HYUN SUK,김현석,KIM, JONG KEUN,김종근,YUN, HYUNG SIK,윤형식,LEE, YOUNG MIN,이영민,KIM, HAENG RAN,김행란,CHO, KANG JIN,조강진,PARK, KYE WONKR,JANG, WOO SEOKKR,KIM, HYUN SUKKR,KIM, JONG KEUNKR,YUN, HYUNG SIKKR,LEE, YOUNG MINKR,KIM, HAENG RANKR,CHO, KANG JINKR
申请号：
KR1020130133350
公开号：
KR1020150051631A
申请日:
2013.11.05
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to a composition containing an extract of black rice as an active ingredient for preventing or treating metabolic bone diseases such as osteoporosis, bone formation disorder, fracture, or the like. A reed extract of the present invention promotes the expression of ALP, osterix, and RUNX2, which are related to the differentiation of osteoblasts, and increases a bone mineral density (BMD) and a bone strength in an ovariectomized osteoporosis animal model, and accordingly, can be used as a medicinal product or a health functional food which is useful for metabolic bone diseases.본 발명은 흑미 추출물을 유효성분으로 하는 골다공증, 골형성 장애 또는 골절 등의 골대사 질환의 예방 또는 치료용 조성물에 관한 것으로, 본 발명의 갈대 추출물은 조골세포의 분화에 관련된 유전자인 ALP, osterix, RUNX2 발현을 증진시키고, 난소절제 골다공증 동물모델에서 골밀도(BMD) 및 골강도를 증가시켜, 골대사 질환에 유용한 의약품 또는 건강기능식품으로 이용될 수 있다.
