In the case of boron neutron capture therapy, it is necessary to send a large amount of 10B to the tumor cell. However, there were no compounds capable of carrying an EPR effect and transporting a large amount of 10B into a tumor cell.A boron containing compound characterized by a stable isotope of boron, a cell permeable peptide (intracellular carrying peptide) and an agglutination inhibitor on the supported particle were selected as selective particles of boron by selective selection of BSH as a stable isotope of boron, and selective invasion to tumor cells It is possible to obtain a boron containing compound having an ability of entering and having no cohesion.Diagram【課題】ホウ素中性子捕捉療法を行う際に、大量に１０Ｂを腫瘍細胞内に送り込む必要がある。しかし、ＥＰＲ効果を奏し、１０Ｂを大量に腫瘍細胞内に運搬できる化合物は従来なかった。【解決手段】担持粒子にホウ素の安定同位体と、細胞透過性ペプチド（細胞内運搬ペプチド）と、凝集阻害剤を担持させたことを特徴とするホウ素含有化合物は、担持粒子に金を選び、ホウ素の安定同位体としてＢＳＨを選ぶことで、腫瘍細胞への選択的な侵入能を有し、なおかつ担持粒子同士が凝集しないホウ素含有化合物を得ることができる。【選択図】図１
