The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with an anti-VEGF antibody for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and an anti-VEGF antibody.本發明係關於非典型岩藻醣化抗CD20抗體與抗VEGF抗體用於治療癌症之組合療法,尤其係關於使用非典型岩藻醣化人類化B-Ly1抗體及抗VEGF抗體治療表現CD20之癌症的組合療法。(無元件符號說明)