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Pansements contenant des hydrogels hydratés et des enzymes
专利权人:
Archimed LLP
发明人:
申请号:
EP06011877.5
公开号:
EP1693073A3
申请日:
2003.04.23
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
A skin dressing, particularly a wound dressing, of layered construction comprising an upper layer, remote from the skin in use including oxidoreductase enzyme, wherein the enzyme is present in hydrated condition, e.g. being present in one or more hydrated hydrogels. The dressing is used by being located on the skin of a human or animal e.g. over a wound. The oxidoreductase enzyme catalyses a reaction that produces hydrogen peroxide from an appropriate substrate, the substrate either being naturally present in body fluids and/or being supplied separately and/or being incorporated into the dressing. The currently preferred oxidoreductase enzyme is glucose oxidase. This catalyses reaction of β-D-glucose substrate to give hydrogen peroxide and gluconic acid. A mixture of oxidoreductase enzymes may be used. The hydrogen peroxide resulting from the reaction catalysed by the oxidoreductase enzyme can undergo reaction (optionally catalysed by the peroxidase enzyme) to produce a variety of species including reactive oxygen intermediates that have antimicrobial properties and that can therefore assist in promoting wound healing.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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