Muhammed Majeed,Kalyanam Nagabhushanam,Anju Majeed,Bani Sarang,Anjali Pandey
申请号:
US14274096
公开号:
US09328330B2
申请日:
2014.05.09
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention discloses the potential of Calebin A in inhibiting adipogenesis and applications thereof in obesity management. The present invention elucidates the potential of Calebin A to favorably modulate biochemical markers associated with obesity. Notable biomodulatory properties of Calebin A include inhibiting leptin production, increasing adiponectin expression and inhibiting local (adipocyte) and systemic inflammation caused by pro-inflammatory cytokines Tumor Necrosis Factor (TNF-α), Interleukin-6 (IL-6) and Interleukin-1 (IL-1β).