The present invention relates to a topical dermatological/pharmaceutical composition comprising BPO wherein the composition is a wash composition with desirable tolerance, stability and foaming properties. The composition comprises: a) Benzoyl peroxide (BPO), b) At least one mild surfactant selected from anionic and/or non-ionic surfactant classes, c) Zinc gluconate, d) Dipotassium glycyrrhizate, e) At least one gelling agent. The composition is preferably in the form of an aqueous gel or an aqueous-alcoholic gel. The invention also concerns the use of such composition for the treatment of dermatological disorders, and in particular in the treatment of acne.