The present Invention provides quinazolin - THF amines as PDE1 inhibitors and their use as a Medicine, in particular for the treatment of neurodegenerative Disorders and Psychiatric DisordersLA PRESENTE INVENCIÓN PROPORCIONA QUINAZOLIN-THF-AMINAS COMO INHIBIDORES DE PDE1 Y SU USO COMO UN MEDICAMENTO, EN PARTICULAR PARA EL TRATAMIENTO DE TRASTORNOS NEURODEGENERATIVOS Y TRASTORNOS PSIQUIÁTRICOS