Described herein are implant delivery systems and methods for controllably deploying an expandable device in a ventricle, the left atrial appendage, or other portion of the heart of a patient. In some embodiments, the implant delivery system includes means for loosening or releasing a suture on a perimeter region of the expandable device in order to control the expansion or contraction of the expandable member. In some such embodiments, loosening or releasing the suture expands the perimeter region of the expandable device to secure the expandable device in the ventricle of the patient, while tightening the suture contracts the perimeter region of the device. The system may include one or more monitoring devices to monitor aspects of the heart, such as hemodynamics.