JASPERS, STEPHEN R.,RIXON, MARK W.,DILLON, STACEY R.,RAMSDELL, FREDERICK J.,KREJSA, CECILE M.,YI, EUGENE C.
申请号：
CA2707026
公开号：
CA2707026C
申请日:
2008.12.08
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Human anti-human IL-21 monoclonal antibodies and thehybridomas that produce them are presented. Certain of these antibodies havethe ability to bind native human IL-21, a mutant recombinat IL-21 proteinand/or peptide regions of human IL-21. These human anti-IL-21 antibodiesare useful in therapeutic treatment of autoimmune and inflammatory diseases,particularly diseases mediated by T follicular helper cells, B cells T H cellsorT H17 cells.
