A secure endotracheal tube holder is provided that is specifically designed to securely hold an endotracheal tube in the neonatal population and that provides stability when used with tape. It is easy to use and replaces non-approved devices such as the post manufacture-modified umbilical cord clamp, which were not intended for securing the endotracheal tube or other products on the market that have high extubation rates. The taberculated inside surfaces of the opening hold the tube in place while a lateral curve provides for easier handling when securing to the face with tape or when the tube requires adjustment. The device is clearly marked with appropriate numeric size indicating the tube size along with a color scheme for visual recognition, and it is constructed from clear or colored plastic to facilitate seeing the markings and depth.