Use of Cistanche tubulosa extract, isoacteoside and/or a pharmaceutical acceptable salt of isoacteoside in the manufacture of a medicament or a food product for protecting muscles, wherein the medicament is particularly used for protecting muscle cell against injury to regulate, treat and/or delay muscle loss, and especially for the muscle loss caused by aging, diseases, and/or cochexia. The food product is a health food, a nutritional supplement food, or a special nutrition food.一種使用管花肉蓯蓉(Cistanche tubulosa)萃取物、異類葉升麻苷、及/或異類葉升麻苷之醫藥上可接受之鹽於製備一藥物或一食品之用途,其中該藥物或食品係用於保護肌肉。該藥物尤其係用於抗肌細胞損傷,以調節、治療及/或延緩肌肉流失,特別是因為老化、疾病及/或惡病質所引起之肌肉流失。該食品係保健食品、營養補充食品或特殊營養食品。