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Benzisoxazole derivatives
专利权人:
Hirohide Noguchi;Isao Sakurada;Chikara Uchida;Nobuaki Waizumi
发明人:
Hirohide Noguchi,Isao Sakurada,Chikara Uchida,Nobuaki Waizumi
申请号:
US11814588
公开号:
US08816090B2
申请日:
2006.02.15
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This invention relates to compounds of the formula (I): wherein A, B, R1, R4, m, and n are each as described herein or a pharmaceutically acceptable salt thereof, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by 5-HT4 receptor activity such as, but not limited to, gastroesophageal reflux disease, gastrointestinal disease, gastric motility disorder, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation, dyspepsia, esophagitis, gastroesophageral disease, nausea, central 10 nervous system disease, Alzheimer's disease, cognitive disorder, emesis, migraine, neurological disease, pain, cardiovascular disorders such as cardiac failure and heart arrhythmia, diabetes and apnea syndrome.
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中国工程科技知识中心
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