The present invention discloses a body fluid drainage device, which is adapted for being mounted on a frame for draining body fluid from an affected portion. The body fluid drainage device includes a body fluid drainage member for draining the body fluid from the affected portion and a body fluid drainage monitoring member detachably coupled to the body fluid drainage member for monitoring the drainage condition, so as to allow medical personnel to directly and/or indirectly utilize the body fluid drainage monitoring member to monitor the drainage condition.