DUBOIS, LAURENT,EVANNO, YANNICK,MACHNIK, DAVID,MALANDA, ANDRE
申请号：
NZ58693809
公开号：
NZ586938A
申请日:
2009.01.20
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
The disclosure relates azabicyclic carboxamide compounds of formula (I), in the form of a base or of an addition salt with an acid, and also in the form of a hydrate or of a solvate, wherein the variables shown in formula (I) are as defined in the specification. The disclosure also relates a process for the preparation of these compounds as well as compositions comprising such compounds and therapeutic methods that utilize such compounds. These compounds are suitable for treating pathologies in which receptors of TRPV1 type are involved and can be used for treating pain, inflammation, metabolic disorders, urological disorders, gynaecological disorders, gastrointestinal disorders, respiratory disorders, psoriasis, pruritus, dermal, ocular or mucous irritations, herpes, zona, multiple sclerosis, depression and cancers.
