The object of the invention is an antibody combined with melanoma cell adhesive (MCAM), which can block the interaction between MCAM and its alliance, namely, the alpha-4 chain of laminina. The invention also relates to a method for using the anti MCAM antibody.La invencion se dirige a anticuerpos que se unen a la molecula de adhesion de celulas de melanoma (MCAM) que son capaces de bloquear la interaccion entre MCAM y su ligando, la cadena alfa-4 de la laminina. La invencion se dirige tambien a metodos de uso de los anticuerpos anti-MCAM descritos