METHODS OF IDENTIFYING MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USE OF SAME TO MODULATE mTORC1

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专利权人:

发明人:

申请号：

EP15840018.4

公开号：

EP3191116A2

申请日:

2015.09.11

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention provides methods of identifying modulators of mTORC1 based upon their effect on GATOR2-Sestrin binding or Sestrin-leucine binding and the use of such modulators to alter mTORC1 activity in a cell and to treat disease and conditions that are effected by mTORC1 activity.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/