Novel 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40

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专利权人:

Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.

发明人:

Furlotti, Guido,Cazzolla, Nicola,Guglielmotti, Angelo,Garofalo, Barbara,Mangano, Giorgina

申请号：

AU2009221083

公开号：

AU2009221083B2

申请日:

2009.03.05

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to Formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40, and to their use in a method for treating or preventing diseases based on the expression of MCP-1, CX3CR1 and p40.

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